Use a transistor as a heater
REC Johnson, B Lora Narayana, and Devender Sundi, Center for Cellular and Molecular Biology, Hyderabad, India - April 19, 2012
You can use an N-channel IRF540 MOSFET to directly heat and control the temperature of a biological sample from ambient to 45°C. Figure 1 shows a simple on/off-type control circuit in which an LM35, IC1, is the temperature sensor, whose output a DPM (digital panel meter) can display. IC2 compares the voltage that VR1 sets with the output of the LM35 to turn on Q2 accordingly, with the positive feedback through R9 providing a small amount of hysteresis. S1 switches the DPM between a set value and the actual temperature readout. You derive the reference voltage from a TL431 shunt regulator (not shown). The LED lights up when Q2 is on.

Be sure to set VR3 to minimum
power during initial power-up; if you
set it for maximum power, you could
apply 24V to Q2’s gate-to-source voltage,
which is rated for a maximum of
only 20V. You can extend the temperature
range by changing the voltage
divider comprising R1, R2, and VR1. The
design includes a safety cutoff circuit
(not shown) in case the temperature
gets too high.Various other options are also possible applications for this circuit. These applications include linear control, pulse-width modulation, and the use of a PID (proportional-integral-derivative) controller, to name a few.
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